Multifocal electroretinogram demonstrated macular toxicity associated with ethambutol related optic neuropathy

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Ethambutol-associated optic neuropathy.

INTRODUCTION Ethambutol is used in the treatment of tuberculosis, which is still prevalent in Southeast Asia, and can be associated with permanent visual loss. We report 3 cases which presented with bitemporal hemianopia. CLINICAL PICTURE Three patients with ethambutol-associated toxic optic neuropathy are described. All 3 patients had loss of central visual acuity, colour vision (Ishihara) a...

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Peripheral neuropathy associated with ethambutol.

A woman developed peripheral neuropathy and optic neuritis while receiving ethambutol in the retreatment of drug-resistant pulmonary tuberculosis. There was prompt improvement in peripheral neuropathy and the ocular symptoms following the withdrawal of the drug. The clinical events in this case suggest that occasionally symptoms of peripheral neuropathy may precede the development of optic neur...

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Multifocal electroretinogram in occult macular dystrophy.

PURPOSE Occult macular dystrophy (OMD) is an unusual macular dystrophy presenting with an essentially normal fundus and fluorescein angiography but with progressive central visual loss. The authors studied the function of local retinal areas in the posterior pole of patients with OMD using multifocal electroretinograms (ERGs). METHODS Multifocal ERGs were recorded using the Visual Evoked Resp...

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Leber Hereditary Optic Neuropathy Associated with Bilateral Macular Holes

Leber hereditary optic neuropathy (LHON) causes visual loss, predominantly in healthy young men. We recently examined a patient who previously had bilateral macular holes and subsequently developed LHON at 74 years of age. Although his central scotomas were initially attributed to the macular holes, his visual acuity declined following an initial improvement after operative closure of the macul...

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The rare ethambutol-induced optic neuropathy

RATIONALE Ethambutol-induced optic neuropathy (EON) is a well-known complication that results from the use of ethambutol. The ocular manifestations of EON include painless loss of central vision and cecocentral scotomas in the visual field. PATIENT CONCERNS A 75-year-old Chinese Han man suffered from this rare ocular disorder because he took ethambutol for about 8 months. DIAGNOSES He was d...

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ژورنال

عنوان ژورنال: British Journal of Ophthalmology

سال: 2005

ISSN: 0007-1161

DOI: 10.1136/bjo.2004.058099